Instruct Events

EMBO: Practical Course "Structural Characterization of Macromolecular Complexes"
Date:04-Jun-2012 1:00 CEST to 25-Sep-2017 9:48 CEST

An Instruct funded courseCourse Overview:This EMBO practical course aims to teach the strategic use of various biochemical and biophysical techniques to facilitate structural studies of macromolecular complexesThe primary focus is on how to produce, purify and characterize multi-subunit protein and protein/nucleic acid complexes for structural analysis.Topics include:expression in bacteria, insect and mammalian cells;affinity methods to purify protein components or entire complexes;biochemical a

Hybrid structural biology approaches
Date:11-Jun-2012 1:00 CEST to 25-Sep-2017 9:48 CEST

An Instruct funded courseCourse Overview:The course will cover theoretical and experimental approaches to Small Angle X-ray Scattering (SAXS), Macromolecular Crystallography (MX) and Electron Microscopy (EM) offered at EMBL Hamburg and EMBL Heidelberg. Combined use of these structural techniques will be demonstrated and discussed.The course is aimed at PhD students and postdocs who have at least a basic understanding of one (or more) of the techniques listed above, and are interested in learning

Computational Tools: Modelling Multi-molecular Assemblies and Protein Design
Date:02-Sep-2012 1:00 CEST to 25-Sep-2017 9:48 CEST

An Instruct funded course2nd – 6th September 2012Registration deadline is July, 15th 2012.  For registration details please contact:Natasha Gruber - Course SecretaryEmail: Natasha.Gruber@weizmann.ac.ilCourse Overview:The goal of the workshop is to introduce the participants to state of the art computational methods (algorithms) for the following:1.      Modeling of macromolecular assemblies based on experimental information obtained from various sources. This

MPIB: Integrative approaches for cellular cryo-electron tomography - Correlative imaging and focused ion beam micromachining
Date:03-Sep-2012 1:00 CEST to 25-Sep-2017 9:48 CEST

An Instruct funded course(Course date TBC)Course Overview:The study of complex biological samples from ‘cellular landscapes to molecular territories’ is essentially a threefold task:Identify features of interestNavigate theseAnd finally, target and capture high-resolution snapshots that represent bona fide cellular events.The first two tasks can be addressed by correlative cryofluorescence microscopy, which offers the possibility to navigate large cellular volumes and to localize specific ce

IBMC: Biomolecular Interactions Analysis
Date:12-Nov-2012 1:00 CET to 25-Sep-2017 9:48 CEST

An Instruct funded courseFinal Course date: Nov 12-16, 2012 Course website - applications now open until July 31, 2012http://www.ibmc.up.pt/interactions2012/ Course Overview:The course aims at introducing high end technologies related to the study of molecular interactions from and in biological systems. The course will cover the whole workflow for kinetics and thermodynamics characterization of binding events, from cutting edge protein expression and purification to high sensitivity b

IGBMC: Production, Purification and Characterization of Macromolecular Complexes
Date:26-Nov-2012 1:00 CET to 25-Sep-2017 9:48 CEST

An Instruct supported courseCourse Overview:This practical training course will cover state-of-the-art technologies for production and purification of macromolecular complexes from endogenous and recombinant sources with an emphasis on methods of studying complex and difficult targets. Hands-on experiments will target over-expression of recombinant assemblies in prokaryotic and eukaryotic hosts as well as purification from endogenous sources using the TAP-tag strategy. Participants will be encou

IGBMC: Production, Purification and Characterization of Macromolecular Complexes
Date:26-Nov-2012 1:00 CET to 25-Sep-2017 9:48 CEST

An Instruct supported courseCourse Overview:This practical training course will cover state-of-the-art technologies for production and purification of macromolecular complexes from endogenous and recombinant sources with an emphasis on methods of studying complex and difficult targets. Hands-on experiments will target over-expression of recombinant assemblies in prokaryotic and eukaryotic hosts as well as purification from endogenous sources using the TAP-tag strategy. Participants will be encou

Diamond Light Source: Cryo Soft X-ray Imaging of Biological Cells
Date:05-Dec-2012 1:00 CET to 25-Sep-2017 9:48 CEST

An Instruct funded eventCourse OverviewDiamond Light Source will hold a workshop to discuss aspects of Cryo Soft X-ray imaging of biological cells. The aim of the workshop will be to bring together both existing and potential new users of the technique and will focus on sample preparation techniques, data collection and processing for soft X-ray tomography and also include a session on the correlation of X-ray data with other complementary (non-X-ray) techniques.The workshop will comprise a seri

Instruct Council Meeting
Date:11-Jan-2013 1:00 CET to 25-Sep-2017 9:48 CEST

Representatives of the Instruct member countries will meet in Brussels the 11th of January 2013 from 11am to 4pm. More information about the venue is available here.

Advanced methods for the integration of other structural data with NMR data
Date:21-Jan-2013 1:00 CET to 25-Sep-2017 9:48 CEST

An Instruct funded courseCourse overview:The course aims at training young researchers in the combined use of data from various structural techniques, such as SAXS, X-ray diffraction or EM, together with NMR data to achieve a deeper understanding of the structural properties of macromolecular systems, from individual proteins to macromolecular adducts. Various methods based on the integration of NMR and SAXS data for the study of the dynamics of multidomain proteins will also be demonstrated.Out

Ceremonial inauguration of the Josef Dadok National NMR Centre
Date:23-Jan-2013 1:00 CET to 25-Sep-2017 9:48 CEST

You are cordially invited to the Ceremonial inauguration of the Josef Dadok National NMR Centre that will be held on January 23, 2013 followed by the scientific symposium on January 24, 2013.For more information and registration details, please click here.

Instruct Executive Committee Teleconference
Date:04-Feb-2013 1:00 CET to 25-Sep-2017 9:48 CEST

Teleconference of the Instruct Executive Committee.

Xmipp Workshop; Martinsried (Germany)
Date:12-Apr-2013 1:00 CEST to 25-Sep-2017 9:48 CEST

The Workshop covers the details of the Xmipp software package that is used for reconstructing 3D maps from a set of randomly oriented particle images. The majority of the workshop consists of hands-on sessions designed to familiarize the attendees with the public-domain Xmipp software.Signing upRegistration: From mid March to end AprilAttendance is free of charge but advance registration is required as space is limited.Online Registration: http://xmipp.cnb.csic.es/twiki/bin/view/Xmipp/MunichApr2

EMBO Practical Course: High throughput Protein Production and Crystallization
Date:15-May-2013 1:00 CEST to 25-Sep-2017 9:48 CEST

Structural proteomic projects have been established world-wide to carry out high throughput structure determination on a genome-wide scale. Crucial to this effort has been the development of HTP technologies for protein production, protein crystallization and improved methods for structure solution by X-ray crystallography. The overall aim of the course will be to review the state-of-the-art in HTP structural biology with an emphasis on methods to study complex targets, including membrane protei

Instruct Biennial Structural Biology Conference
Date:22-May-2013 1:00 CEST to 25-Sep-2017 9:48 CEST

The first Instruct Biennial Structural Biology Meeting at EMBL Heidelberg Advance Training Centre, 22nd to 24th of May 2013, will showcase integrative structural biology and its impact on biological research. The program will include sessions that represent recent structural biology highlights, emerging methods and technologies and results of biomedical importance. Continue reading

Instruct Council
Date:24-May-2013 1:00 CEST to 25-Sep-2017 9:48 CEST

Meeting of the Instruct Council

Instruct Executive Committee Meeting
Date:24-May-2013 1:00 CEST to 25-Sep-2017 9:48 CEST

Meeting of the Instruct Executive Committee

Instruct Executive Committee Teleconference
Date:23-Jul-2013 1:00 CEST to 25-Sep-2017 9:48 CEST

Instruct Executive Committee Teleconference

Getting the best from your structural data: beyond black boxes
Date:18-Sep-2013 1:00 CEST to 25-Sep-2017 9:48 CEST

An Instruct supported courseThe course is intended primarily for post-doctoral researchers and Ph.D. students in structural biology. The goal is that the participants improve their theoretical background and gain hands-on experience in the structure determination of “difficult macromolecules” by singlecrystal X-ray crystallography. The course will cover state-of-the-art methodology for data processing with emphasis on integration of different methods to solve structures of macromolecular com

Getting the best from your structural data: beyond black boxes
Date:18-Sep-2013 1:00 CEST to 25-Sep-2017 9:48 CEST

An Instruct supported courseThe course is intended primarily for post-doctoral researchers and Ph.D. students in structural biology. The goal is that the participants improve their theoretical background and gain hands-on experience in the structure determination of “difficult macromolecules” by singlecrystal X-ray crystallography. The course will cover state-of-the-art methodology for data processing with emphasis on integration of different methods to solve structures of macromolecular com

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